^{7th International conference on} Ayurveda, Homeopathy and Chinese Medicine May 18-19, 2017 Munich, Germany

Introduction: Chaos expresses the multiplicity of events in a holds infinity, synergy, relationships and expressions. It is the principle of possibilities and also to understand the cases from multiple perspectives. In the holistic interpretation, everything is associated with the concrete experience of the totality that, through processes allow for understanding, constant to other holds. Holistic is constant interaction, historical realization and chaos, understanding this as fullness of possibilities dynamism, optimism, etc. Hence also that in holistic limits rather than arrival points or fences of content, are realities to transcend points to exceed understandings to develop.

General & Specific Objectives: General objectives of this are to make known basic human behavior patterns, as it has a totalizing, integral, holistic character. Specific objectives are: 1. Determining and knowing the different paradigms to integrate them in more complete contexts in the therapeutic work, 2. Provide patients with the necessary awareness at the spiritual, moral, and social levels

of guidelines and behaviors useful for maintaining health and progressing to an optimal level.

Conclusions: Every patient is anxious to believe in something for which millions of people in the world are spiritually hungry. They are seeking the fundamental truth that man is a spiritual being who is suppressed and he must be in communion with the Divine source of all healing. This is surely the meaning of the way, the truth, and the life. To perfect our human existence, we must have knowledge of our place, which can happen if we first understand nature in itself.

Thiana Tanaka graduated in Veterinary Medicine in 2008, and has been dedicating herself to Veterinary Rehabilitation. She specialized in Veterinary Physiotherapy

and Acupuncture and was trained in Tui Na, Japanese Acupuncture and Acutonics. Since 2013, she has been involved in the treatment of emotional issues of animals through Microphysiotherapy and Biological Reading. Recently in 2016, she has dedicated herself to the studies of telepathic communication with animals and the therapeutic technique of Thetahealing.

Microkinesiotherapy is a technique of manual therapy developed in France in the 80s, based on embryology, phylogenesis and ontogenesis. It assumes that all the cells of our body are able of storing memories in all periods of life, and even ancestral information. Moreover, it says that every living being has an ability to adapt, self-defend and self-heal, seeking balance to protect itself and equalize to the outside environment. The body suffers aggressions of all kinds (toxic, chemical, physical, emotional or environmental) and in different intensities. However, if the aggression is severe and the body does not react effectively, a memory, or pathological scar of the event in the tissues will be recorded. This scar alters the vitality and function of the battered tissue,

which may manifest one or more symptoms on the injured location and generate physical, psychic or emotional disorder. Through different micro-specific palpatory movements and following body maps developed by the creators of Micro kinesiotherapy, it allows the therapist to identify the traces left by these aggressions in the different tissues of the organism. Once the scar is identified and localized, the therapist reinforms the body so that it is stimulated to trigger the processes of self-healing, aiding in the restoration of

vitality and tissue function. The work of "cleaning" that the body initiates may cause a slight fatigue during 1 or 2 days, being indicated that the patient does not make physical effort. Physical symptoms such as diarrhea, vomiting, increased pain, fever, emotional crisis may occur upto two days after the session. These manifestations occur as a sign of liberation from the aggressor memories. The patient, therefore, should rest and allow self-heal of the body, with the minimum possible of drug interference.

Wageesha N D A received his Undergraduate Education from the Institute of Chemistry Ceylon, Sri Lanka, and his MPhil in Biochemistry from University of Sri Jayawardenapura, Sri Lanka. He is currently a Senior Lecturer in Biochemistry and Chemistry at Department of Biochemistry and Chemistry, the Faculty of Medicine, South Asian Institute of Technology and Medicine, Sri Lanka. His current research interests involve the cancer research and currently working towards his PhD in the field of development of novel anti-cancer drug based on traditional medicinal knowledge. His work has been presented at scientific conferences and published in journals. He received “Kandiah Memorial Graduateship Award” for Post Graduate research from the Institute of Chemistry, Ceylon in 2010 for his research work.

Le Pana Guliya (LPG) is a polyherbal formulation which is used to treat different types of cancers in traditional medicine. In this study, we describe in vitro efficacy and mechanism of action of LPG on four cancer cell lines (HepG2, HeLa, MCF-7 and RD) compared with a normal cell line CC1. The MTT, LDH assays and protein synthesis were used to study antiproliferative activity of LPG while NO synthesis and GSH content were assayed to determine the oxidative stress exerted by LPG. Rhodamine 123 staining,

caspase 3 activity, DNA fragmentation and microscopic examination of cells stained with ethidium bromide/acridine orange were used to identify the apoptosis mechanisms associated with LPG. The LPG showed the potent antiproliferative effect against all tested cancer cells with an EC50 value of 2.72±0.36, 19.03±2.63, 24.90±2.03 and 17.57±2.8 μg/mL for HepG2, HeLa, MCF-7 and RD cells respectively for MTT assay after 24 h treatment. In contrast, CC1 cells showed an EC50 value of 213.07±7.71 μg/mL. Similar results were observed for LDH release. A dose dependent decrease in protein synthesis was shown in both cancer cell types compared to CC1 cells. The reduction of GSH content and elevation of cell survival with exogenous GSH prove that the LPG act via induction of oxidative stress. LPG also stimulates the production of NO and mediates oxidative stress. Rhodamine 123 assay shows the mitochondrial involvement in cell death by depletion of Δψ inducing downstream events in apoptosis. This results in increase in caspase-3 activity and eventually DNA fragmentation and LPG induced apoptotic cell death. In conclusion, the present study suggested that the LPG exerted an anticancer activity via oxidative stress dependent apoptosis. Therefore present study provides the scientific proof of the traditional knowledge in using LPG as an anticancer agent.

Nathalie Guillaume DAOM, LAc received her Clinical Doctorate in Pain Management & Oncology from Bastyr University. She has done advanced rotations in China where she had extensive Orthopedic and Cancer Care training at Long Hua Traditional Chinese Medicine Hospital in Shanghai and Sichuan Integrative Eastern and Western Hospital in Chengdu. Her experience in the performing arts has influenced her interest in a creative approach to the clinical practice using lifestyle changes, nutrition, movement therapy and meditation as medicine. She has extensively researched the therapeutic benefits of Medical Qigong in chronic back pain and is dedicated to promoting the benefits of holistic health to the community through education and service. She is currently Adjunct Faculty for the Graduate School of Oriental Medicine at the New York College of Health Professions and practices in New York City where she is the CEO and Medical Director of Healing Happy Hour.

Statement of the Problem: Chronic Back Pain (CBP) is a common symptom bothering the elderly population seeking medical care. The most common strategy suggested for the relief of this condition is pharmacological and causes harmful side effects. Yi Ren Medical Qigong (YRMQ) has demonstrated that just one single application of this gentle exercise could reduce chronic pain in elderly people. The objective of this clinical trial was to evaluate the effectiveness of Qi therapy in decreasing pain or discomfort.

Methodology & Theoretical Orientation: A group of seven participants with CBP took part in weekly one-hour group Qigong sessions in addition to practicing a shorter version of the exercises at home twice a week. Pain intensity was evaluated using a Visual Analog Scale (VAS), showing reduction of symptoms. Other assessment tools such as the Roland Morris Disability Questionnaire (RMDQ) and the Brief Pain Inventory (BPI) scales were used to measure the pain reduction over the course of the 5-week trial. Findings: The participants were very motivated and most of them attended without missing a week. The mean adjusted low back intensity using the assessment tools showed a significant reduction. No serious or life-threatening adverse effects were found.

Conclusions & Significance: Qigong has proven to provide at least in the short term some reduction of pain and pain medication use. Our preliminary efficacy results were consistent with previous Qigong studies showing improvement of back pain via assessment score changes, but not enough significant statistical evidence relevant to prove the replicable efficacy of the proposed exercises. Conducting a The 5-week pilot trial of Qigong exercises for an elderly population sample with CBP was moderately feasible.

Vascular dementia (VD) is the most common form of dementia in the elderly. However, little is understood about the roles of microRNAs (miRNAs) in cognitive impairment in early VD. Here, rats with 4 weeks chronic ischemia showed early impaired acquisition of spatial learning in Morris water maze test. We further investigated the roles of miRNAs in cognitive impairment. The

miRNA expression microarrays on RNA extracted from the hippocampus of rats with 4 weeks chronic ischemia and control rats were used. Real-time reverse transcription PCR was conducted to verify the candidate miRNAs discovered by microarray analysis. The data showed that miR-210 was increased significantly in the hippocampus of rats with 4 weeks chronic ischemia, which were concomitant with that rats displayed a significant synaptic loss and cognitive deficits. Bioinformatic analysis predicted that snap25 mRNA is targeted by miR-210. Overexpression of miR-210 lowers the levels of snap25 and synaptic proteins expression in PC12 cells damage induced by serum-free. In contrast, suppression of miR-210 by miR-210 inhibitor significantly results in higher levels of snap25 and synaptic proteins expression. Taken together, miR-210 is involved in cognitive impairment in rats with chronic ischemiainduced vascular dementia through regulation of snap25.

Ramanand Ramadasan from Calicut Kerala, India graduated in English Literature and British and World History, Post Graduate in Medical and Psychiatric Social Work from the University of Calicut. Obtained MPhil in Social Sciences in Health on the topic Pluralism with in Pluralism -Analysing the Sociology of Ayurvedic practice in Kerala from the Centre for Social Medicine and Community Health, Jawaharlal Nehru University New Delhi. Currently undergoing PhD from the same University on the Topic of Pluralism in Yoga. I have been working on the field of Traditional Medicine for the last three years and have delivered lectures and published papers on the same topic.

Existence of pluralist health care is a global phenomenon. In India; Ayurveda, Yoga and Naturopathy, Unani, Siddha, Sowa Rigpa and Homeopathy co-exist with Biomedicine. This paper maps and expresses the different forms of medical practices within the system of Ayurveda. In a sense it is an attempt to look at the pluralism within pluralism. The paper has two parts, the first part is based on the primary research conducted at northern Kerala, India, popularly known as Malabar. The nuances of each system ranging from Kalaripayattu (Martial arts and healing therapy) Paramparya Vaidyans (Traditional healers) Visha Chikitskaks (Snake bite and other poison healers) and Marma Chikitsaks are presented. Along with the interactions of these, different practices with state sponsored Ayurveda is discussed under the sub headings of 1) Ayurveda as a monolith – problems and prospects in homogenizing 2) Terms

of engagement between Local health traditions and Ayurveda- Who is setting the terms? 3) Knowledge transfer – Appropriation or incorporation? 4) Asymmetrical Pluralism- State response to local health traditions. 5) The question of legitimacy – Perspectives from traditional local health practitioners. Second part of the paper deals with the idea of integration of Indigenous systems to heath care. This part is based on secondary sources and it is looking at the ‘Integration Ideas’ used in Indian health sector after

the establishment of Ministry for AYUSH (Ayurveda, Yoga and Naturopathy, Unani, Siddha, Sowa Rigpa and Homeopathy). The theme is discussed under various subheadings such as, The history of Ayurveda and its status during Colonial times and Post- Independence. Philosophical tenets, The Rational Irrational dichotomy- Evidence based medicine and Randomized Control Trial,

Areas of interaction with Biomedicine, Biomedicalization of Ayurveda, Levels of Integration, Health security and Ayurveda.

Hadar S Faizy is an expert in Plant Extract and Tissue Culture. Currently she is PhD student jointly supervised by Prof. Muraleedharan G Nair, PhD, CChem, FRSC, Senior associate to the Dean of CANR, Horticulture at Michigan State University. She worked in Bioactive Natural Products and Phytoceuticals Laboratory in the Department of Horticulture at Michigan State University. Her project is “Evaluation of phytochemical analysis, hypoglycemic and antioxidant activities of Nasturtium officinale plants produced by tissue culture techniques”. At the meantime, she is working as a Lecturer at the Department of Horticulture/College of Agriculture, University of Duhok, Kurdistan Region of Iraq.

Statement of the Problem: Watercress (Nasturtium officinale) has been long used as a home remedy by different cultures as medicinal plant. The aim of this study is to investigate the antioxidant activity of watercress.

Methodology & Theoretical Orientation: Hexane and methanol extracts of plant dried materials were used which have been collected from three different villages in Duhok/Kurdistan Region of Iraq. The relationship between secondary metabolites contents and antioxidants were tested by MTT assay.

Findings: The highest antioxidant activity was observed in aerial parts at low altitude at 459 m Zawa village. Low amount of steroids compounds of methanol extract accompanied the weakest activity of antioxidant in the plants that were collected from Kanimasea village at 1340 m altitude. The isolation and purification were done for the hexane and methanol aerial parts extracts. As a result, white crystalline powder was obtained which was conformed to physical, chemical and spectral identification by 1H-NMR; the compound was identified as ß-sitosterol.

Conclusion & Significance: Due to antioxidant potential of Nasturtium officinale extract, it might find application in the prevention of free radical related diseases.